N-Acetylcysteine amide | Tocris Bioscience 5619/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

N-Acetylcysteine amide

catalog :

5619/10

quantity :

10 mg (also 50 mg)

price :

191 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Tao T, Deng P, Wang Y, Zhang X, Guo Y, Chen W, et al. Microengineered Multi-Organoid System from hiPSCs to Recapitulate Human Liver-Islet Axis in Normal and Type 2 Diabetes. Adv Sci (Weinh). 2022;9:e2103495 pubmed publisher
Gutierrez E, Richardson D, Jansson P. The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. J Biol Chem. 2014;289:33568-89 pubmed publisher

product information

brand :

Tocris

master code :

5619

SKU :

5619/10

rank :

0.061

product name :

N-Acetylcysteine amide

description :

Glutathione (GSH) precursor; neuroprotective

target :

Additional Antioxidant Compounds

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

N -Acetylcysteine amide is a glutathione (GSH) precursor and cell-permeable antioxidant. N -Acetylcysteine amide replenishes intracellular Glutathione (GSH). N -Acetylcysteine amide directly reduces intracellular Glutathione disulfide (GSSG) to GSH without glutathione peroxidase. N -Acetylcysteine amide has anti-inflammatory activity through regulation of activation of NF- B and HIF-1 , as well as modulation of reactive oxygen species. N -Acetylcysteine amide improves neuronal mitochondrial bioenergetics, reduces tissue damage and enhances functional recovery following spinal cord injury in rats. N -Acetylcysteine amide also enhances behavioral recovery in rats following traumatic brain injury. Neuroprotective. . For more information about how N-Acetylcysteine amide may be used, see our protocol: 3D Culture of Lung Alveolar Cells

extended description :

Glutathione (GSH) precursor; neuroprotective

chemical name text :

(2R)-2-(Acetylamino)-3-mercaptopropanamide

formula :

C 5 H 10 N 2 O 2 S

formula text :

C5H10N2O2S

cas num :

38520-57-9

USD :

191 USD

product details :

Glutathione (GSH) precursor; neuroprotective

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage