AZD 9272 | Tocris Bioscience 5613 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZD 9272

catalog :

5613

quantity :

10 mg (also 50 mg)

price :

164 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5613

SKU :

5613/10

product name :

AZD 9272

description :

Potent and selective mGlu5 antagonist; brain penetrant

target :

Group I mGluR Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

284.22

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective mGlu5 antagonist (IC50 values are 2.6 and 7.6 nM for rat and human receptors, respectively). Exhibits 3900-fold selectivity for mGlu5 over other mGlu receptors. Also selective over a panel of other targets. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.

catalog number base :

5613

product keywords :

AZD9272 mGlu5 antagonists metabotropic glutamate receptors orally bioavailable brain penetrant potent selective Glutamate (Metabotropic) Group I Receptors 5613,

extended description :

Potent and selective mGlu5 antagonist; brain penetrant

chemical name text :

3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile

formula :

C 14 H 6 F 2 N 4 O

formula text :

C14H6F2N4O

cas num :

327056-26-8

2020 USD :

159

2021 USD :

164 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage