AZD 9272 | Tocris Bioscience 5613/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AZD 9272

catalog :

5613/10

quantity :

10 mg (also 50 mg)

price :

185 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5613 - AZD 9272 C14H6F2N4O CAS No. 327056-26-8

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5613

SKU :

5613/10

product name :

AZD 9272

description :

Potent and selective mGlu5 antagonist; brain penetrant

target :

Group I mGluR Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at RT

observed molecular weight :

284.22

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AZD 9272 is a potent and selective mGlu5 antagonist (IC50 values are 2.6 and 7.6 nM for rat and human receptors, respectively). Exhibits 3900-fold selectivity for mGlu5 over other mGlu receptors. Also selective over a panel of other targets. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.

product keywords :

AZD9272 mGlu5 antagonists metabotropic glutamate receptors orally bioavailable brain penetrant potent selective Glutamate (Metabotropic) Group I Receptors 5613,

extended description :

Potent and selective mGlu5 antagonist; brain penetrant

chemical name text :

3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile

formula :

C14H6F2N4O

formula text :

C14H6F2N4O

cas num :

327056-26-8

USD :

205

USD 2025 :

185 USD

product details :

Potent and selective mGlu5 antagonist; brain penetrant

more info or order :

Tocris Bioscience product webpage