product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
BS 181 dihydrochloride
catalog :
5608/10
quantity :
10 mg (also 50 mg)
price :
216 USD
more info or order :
image
image 1 :
Tocris Bioscience 5608/10 image 1
Cat.No. 5608 - BS 181 dihydrochloride C22H32N6.2HCl CAS No. 1883548-83-1
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
5608
SKU :
5608/10
product name :
BS 181 dihydrochloride
description :
Selective cdk7 inhibitor
target :
Cyclin-dependent Kinase Inhibitors
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Store at +4°C
observed molecular weight :
453.45
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
BS 181 dihydrochloride is a selective cdk7 inhibitor (IC50 = 21 nM). Displays >40-fold selectivity for cdk7 over other cdks. Promotes cell cycle arrest and apoptosis in a range of cancer cells in vitro and inhibits MCF-7 tumor xenograft growth in mice.
product keywords :
cyclin-dependent kinase 7 cdk7 BS-181 inhibitors cancer apoptosis activating 1397219-81-6 inhibits Cyclin-dependent Kinase Transcriptional CDKs 5608,
extended description :
Selective cdk7 inhibitor
chemical name text :
N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride
formula :
C22H32N6.2HCl
formula text :
C22H32N6.2HCl
cas num :
1883548-83-1
USD :
240
USD 2025 :
216 USD
product details :
Selective cdk7 inhibitor
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK