GNF 7 | Tocris Bioscience 5607 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GNF 7

catalog :

5607

quantity :

10 mg (also 50 mg)

price :

172 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5607

SKU :

5607/10

product name :

GNF 7

description :

Ras signaling inhibitor; inhibits Ack1 and GCK

target :

Ras GTPase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

547.53

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ras signaling inhibitor; inhibits Ack1 and germinal center kinase (GCK). Suppresses proliferation, and induces cell cycle arrest and apoptosis in leukemia cells harboring NRAS mutations. Prolongs survival in a leukemia cell xenotransplantation model in mice.

catalog number base :

5607

product keywords :

GNF7 RAS inhibitors inhibits Ack1 germinal centre kinases GCK leukemia TNK2 Ack1 Ras GTPases 5607, Ras, GTP ase

extended description :

Ras signaling inhibitor; inhibits Ack1 and GCK

chemical name text :

N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide

formula :

C 28 H 24 F 3 N 7 O 2

formula text :

C28H24F3N7O2

cas num :

839706-07-9

2020 USD :

165

2021 USD :

172 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage