LOC14 | Tocris Bioscience 5606 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LOC14

catalog :

5606

quantity :

10 mg (also 50 mg)

price :

151 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Chamberlain N, Korwin Mihavics B, Nakada E, Bruno S, Heppner D, Chapman D, et al. Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics. Redox Biol. 2019;22:101129 pubmed publisher

product information

brand :

Tocris

master code :

5606

SKU :

5606/10

product name :

LOC14

description :

High affinity protein disulfide isomerase (PDI) modulator

target :

Protein Disulphide Isomerase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

317.41

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity protein disulfide isomerase (PDI) modulator (Kd = 62 nM). Forces PDI to adopt an oxidized conformation and suppresses its activity. Neuroprotective.

catalog number base :

5606

product keywords :

LOC14 High affinity protein disulfide isomerase PDI allosteric modulator Huntington disease Protein Disulfide Isomerase 5606, Protein Disulfide Isomerase

extended description :

High affinity protein disulfide isomerase (PDI) modulator

chemical name text :

2-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]methyl]-1,2-benzisothiazol-3(2H)-one

formula :

C 16 H 19 N 3 O 2 S

formula text :

C16H19N3O2S

cas num :

877963-94-5

2020 USD :

145

2021 USD :

151 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage