(-)-JQ1 | Tocris Bioscience 5603 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

(-)-JQ1

catalog :

5603

quantity :

10 mg

price :

346 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Andrieu G, Shafran J, Smith C, Belkina A, Casey A, Jafari N, et al. BET protein targeting suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer and elicits anti-tumor immune response. Cancer Lett. 2019;465:45-58 pubmed publisher
Perry M, Durham A, Austin P, Adcock I, Chung K. BET bromodomains regulate transforming growth factor-Î²-induced proliferation and cytokine release in asthmatic airway smooth muscle. J Biol Chem. 2015;290:9111-21 pubmed publisher

product information

brand :

Tocris

master code :

5603

SKU :

5603/10

product name :

(-)-JQ1

description :

Negative control for (+)-JQ1

target :

Bromodomain Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

456.99

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inactive control for (+)-JQ1 . Exhibits no significant interaction with BRD1-4 or a panel of other bromodomains. . Active Enantiomer also available.

catalog number base :

5603

product keywords :

inactive analogs negative controls bromodomains BRD1 BRD2 BRD3 BRD4 Bromodomains 5603,

extended description :

Negative control for (+)-JQ1

chemical name text :

(6R)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester

formula :

C 23 H 25 ClN 4 O 2 S

formula text :

C23H25ClN4O2S

cas num :

1268524-71-5

2020 USD :

335

2021 USD :

346 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage