Spadin | Tocris Bioscience 5594 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Spadin

catalog :

5594

quantity :

1 mg

price :

173 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Fernández Fernández D, Cadaveira Mosquera A, Rueda Ruzafa L, Herrera Pérez S, Veale E, Reboreda A, et al. Activation of TREK currents by riluzole in three subgroups of cultured mouse nodose ganglion neurons. PLoS ONE. 2018;13:e0199282 pubmed publisher

product information

brand :

Tocris

master code :

5594

SKU :

5594/1

product name :

Spadin

description :

Potent K2P2.1 (TREK-1) channel blocker

target :

Two-P Potassium Channels Blockers

category :

Peptides

unit size :

1 mg

observed molecular weight :

2012.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Potent TREK-1 channel blocker (IC50 = 71 nM). Enhances dorsal raphe nucleus 5-HT neurotransmission in mice. Induces hippocampal CREB activation and neurogenesis in adult mice. Exhibits antidepressant effects in mouse models of depression. Brain penetrant.

catalog number base :

5594

product keywords :

potent TREK-1 channels inhibits inhibitors depression antidepressants CREB neurotensin receptors NTSR3 gp95 sortilin K2P KCNK2 Two-P Potassium Channels 5594,

extended description :

Potent K2P2.1 (TREK-1) channel blocker

formula :

C 96 H 142 N 26 O 22

formula text :

C96H142N26O22

cas num :

1270083-24-3

2020 USD :

166

2021 USD :

173 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage