Spadin | Tocris Bioscience 5594/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Spadin

catalog :

5594/1

quantity :

1 mg

price :

216 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Fernández Fernández D, Cadaveira Mosquera A, Rueda Ruzafa L, Herrera Pérez S, Veale E, Reboreda A, et al. Activation of TREK currents by riluzole in three subgroups of cultured mouse nodose ganglion neurons. PLoS ONE. 2018;13:e0199282 pubmed publisher

image

image 1 :

Cat.No. 5594 - Spadin Tyr-Ala-Pro-Leu-Pro-Arg-Trp-Ser-Gly-Pro-Ile-Gly-Val-Ser-Trp-Gly-Leu-Arg CAS No. 1270083-24-3

product information

brand :

Tocris

MasterCode :

5594

SKU :

5594/1

product name :

Spadin

target :

Two-P Potassium Channels Blockers

category :

Peptides

unit size :

1 mg

purity :

95%

observed molecular weight :

2012.34

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Spadin is a potent TREK-1 channel blocker (IC50 = 71 nM). Enhances dorsal raphe nucleus 5-HT neurotransmission in mice. Induces hippocampal CREB activation and neurogenesis in adult mice. Exhibits antidepressant effects in mouse models of depression. Brain penetrant.

extended description :

Potent K2P2.1 (TREK-1) channel blocker

formula :

C 96 H 142 N 26 O 22

formula text :

C96H142N26O22

cas num :

1270083-24-3

USD :

216 USD

product details :

Potent K2P2.1 (TREK-1) channel blocker

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage