BI 9564 | Tocris Bioscience 5590/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BI 9564

catalog :

5590/10

quantity :

10 mg

price :

224 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Ahmed N, Gatchalian J, Ho J, Burns M, Hah N, Wei Z, et al. BRD9 regulates interferon-stimulated genes during macrophage activation via cooperation with BET protein BRD4. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher

image

image 1 :

Cat.No. 5590 - BI 9564 C20H23N3O3 CAS No. 1883429-22-8

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5590

SKU :

5590/10

product name :

BI 9564

description :

Potent and selective BRD9 and BRD7 inhibitor; orally active

target :

Bromodomain Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Store at -20°C

observed molecular weight :

353.41

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BI 9564 is a potent and selective BRD9 and BRD7 inhibitor (Kd values are 14 and 239 nM, respectively). Exhibits selectivity for BRD9/7 over 48 other bromodomains, 324 kinases and 55 GPCRs. Inhibits proliferation of AML cell lines in vitro and reduces AML tumor xenograft growth in vivo . Cell permeable and orally active.

product keywords :

BI9564 BRD9 BRD7 potent selective inhibitors inhibits bromodomains orally active Bromodomains 5590,

extended description :

Potent and selective BRD9 and BRD7 inhibitor; orally active

chemical name text :

4-[4-[(Dimethylamino)methyl]-2,5-dimethoxyphenyl]-2-methyl-1,2-dihydro-2,7-naphthyridin-1-one

formula :

C20H23N3O3

formula text :

C20H23N3O3

cas num :

1883429-22-8

USD :

248

USD 2025 :

224 USD

product details :

Potent and selective BRD9 and BRD7 inhibitor; orally active

more info or order :

Tocris Bioscience product webpage