WAY 181187 oxalate | Tocris Bioscience 5589/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

WAY 181187 oxalate

catalog :

5589/10

quantity :

10 mg (also 50 mg)

price :

272 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Sheu S, Upadhyayula S, Dupuy V, Pang S, Deng F, Wan J, et al. A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. Cell. 2022;185:3390-3407.e18 pubmed publisher
Nagata M, Yokooji T, Nakai T, Miura Y, Tomita T, Taogoshi T, et al. Blockade of multiple monoamines receptors reduce insulin secretion from pancreatic β-cells. Sci Rep. 2019;9:16438 pubmed publisher

image

image 1 :

Cat.No. 5589 - WAY 181187 oxalate C15H13ClN4O2S2.C2H2O4 CAS No. 1883548-85-3

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

5589

SKU :

5589/10

product name :

WAY 181187 oxalate

description :

High affinity and selective 5-HT6 agonist

target :

5-HT6 Receptor Agonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Desiccate at RT

observed molecular weight :

470.91

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

WAY 181187 oxalate is a high affinity and selective 5-HT6 agonist (Ki = 2.2 nM). Displays 60-fold selectivity over other 5-HT and monoamine receptors. Increases firing rate of 5-HT neurons. Modifies sleep and wakefulness profiles following direct injections into the dorsal raphe nucleus, in vivo . Orally bioavailable.

product keywords :

WAY181187 oxalate 554403-49-5 High affinity and selective 5-HT6 agonists activates sleep serotonin receptors serotonergic 5-HT6 Receptors 5589,

extended description :

High affinity and selective 5-HT6 agonist

chemical name text :

1-[(6-Chloroimidazo[2,1-b]thiazol-5-yl)sulfonyl]-1H-indole-3-ethanamine oxalate

formula :

C15H13ClN4O2S2.C2H2O4

formula text :

C15H13ClN4O2S2.C2H2O4

cas num :

1883548-85-3

USD :

264

USD 2025 :

272 USD

product details :

High affinity and selective 5-HT6 agonist

more info or order :

Tocris Bioscience product webpage