5585/10 | Tocris Bioscience 5585/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5585/10

catalog :

5585/10

quantity :

10 mg (also 50 mg)

price :

183 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Soundararajan A, Ghag S, Vuda S, Wang T, Pattabiraman P. Cathepsin K Regulates Intraocular Pressure by Modulating Extracellular Matrix Remodeling and Actin-Bundling in the Trabecular Meshwork Outflow Pathway. Cells. 2021;10: pubmed publisher

image

image 1 :

Cat.No. 5585 - Balicatib C23H33N5O2 CAS No. 354813-19-7

product information

master code :

5585

SKU :

5585/10

product name :

Balicatib

unit size :

10 mg (also 50 mg)

description :

Potent and selective cathepsin K inhibitor

target :

Synthetic Cathepsin Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

411.54

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Balicatib is a potent and selective cathepsin K inhibitor (IC50 values are 1.4, 56 and 480 nM for human, rat and mouse cathepsin K, respectively). Exhibits 300-fold selectivity for cathepsin K over cathepsins L, B and S. Long term supratherapeutic dosing increases tissue levels of cathepsins L and B in rats.

top caption :

Potent and selective cathepsin K inhibitor

extended description :

Potent and selective cathepsin K inhibitor

chemical name text :

N-[1-(Cyanomethylcarbamoyl)cyclohexyl]-4-(4-propylpiperazin-1-yl)benzamide

formula :

C23H33N5O2

formula text :

C23H33N5O2

cas num :

354813-19-7

USD :

183 USD

product details :

Potent and selective cathepsin K inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage