TAT-cyclo-CLLFVY | Tocris Bioscience 5582 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TAT-cyclo-CLLFVY

catalog :

5582

quantity :

1 mg

price :

270 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Miranda E, Nordgren I, Male A, Lawrence C, Hoakwie F, Cuda F, et al. A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. J Am Chem Soc. 2013;135:10418-25 pubmed publisher

product information

brand :

Tocris

master code :

5582

SKU :

5582/1

product name :

TAT-cyclo-CLLFVY

description :

Selective HIF-1 dimerization inhibitor

target :

HIF Inhibitors

category :

Peptides

unit size :

1 mg

observed molecular weight :

2559.1

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1 , but not HIF-2 , with HIF-1 (IC50 = 1.3 M) . Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cancer cells in vitro . Also reduces tubularization of hypoxic HUVECs.

catalog number base :

5582

product keywords :

HIF-1a 1b 1beta 1alpha hypoxia inducible factor cancer angiogenesis antiangiogenic dimerization inhibitors inhibits Hypoxia Inducible Factors 5582, Hypoxia Inducible Factors, Hypoxia Inducible Factor

extended description :

Selective HIF-1 dimerization inhibitor

formula :

C 111 H 188 N 42 O 24 S 2

formula text :

C111H188N42O24S2

cas num :

1446322-66-2

2020 USD :

259

2021 USD :

270 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage