Lei-Dab 7 | Tocris Bioscience 5571 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Lei-Dab 7

catalog :

5571

quantity :

100 ug

price :

352 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Sargin D, Oliver D, Lambe E. Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels. elife. 2016;5: pubmed publisher

product information

brand :

Tocris

master code :

5571

SKU :

5571/100U

product name :

Lei-Dab 7

description :

High affinity and selective KCa2.2 (SK) blocker

target :

Ca2+-Activated Potassium Channel Blockers

category :

Peptides

unit size :

100 ug

observed molecular weight :

3392.06

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

High affinity, selective KCa2.2 (SK2) channel blocker (Kd = 3.8 nM). Exhibits 200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, IK, Kv and Kir2.1. Increases theta-burst responses and increases LTP in rat hippocampal slices in vitro . Convulsive in vivo .

catalog number base :

5571

product keywords :

Lei-Dab7 selective potent small conductance calcium activated potassium channels K+ Ca2+ inhibitors inhibits KCa2.2 SK2 blockers Ca2+-Activated Potassium Channels 5571,

extended description :

High affinity and selective KCa2.2 (SK) blocker

formula :

C 141 H 236 N 46 O 39 S 6

formula text :

C141H236N46O39S6

cas num :

1061556-49-7

2020 USD :

335

2021 USD :

352 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage