5570/10 | Tocris Bioscience 5570/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5570/10

catalog :

5570/10

quantity :

10 mg (also 50 mg)

price :

213 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Hortle E, Tran V, Wright K, Fontaine A, Pinello N, O Rourke M, et al. OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection. Life Sci Alliance. 2022;5: pubmed publisher
Qiu Z, Dong B, Guo W, Piotr R, Longmore G, Yang X, et al. STK39 promotes breast cancer invasion and metastasis by increasing SNAI1 activity upon phosphorylation. Theranostics. 2021;11:7658-7670 pubmed publisher
Lu D, Hannemann A, Wadud R, Rees D, Brewin J, Low P, et al. The role of WNK in modulation of KCl cotransport activity in red cells from normal individuals and patients with sickle cell anaemia. Pflugers Arch. 2019;471:1539-1549 pubmed publisher

image

image 1 :

Cat.No. 5570 - STOCK2S 26016 C20H19N3O2 CAS No. 332922-63-1

product information

master code :

5570

SKU :

5570/10

product name :

STOCK2S 26016

unit size :

10 mg (also 50 mg)

description :

Lysine deficient protein kinase (WNK) signaling inhibitor

target :

Other Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

333.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

STOCK2S 26016 is a lysine deficient protein kinase (WNK) signaling inhibitor (IC50 = 16 M). Inhibits binding of WNK1 and WNK4 to SPAK and phosphorylation of downstream transporters, NKCC1 and NCC, in mouse vascular smooth muscle and distal convoluted tubule cell cultures exposed to hypotonic shock, respectively. Inhibits STK39 activation; inhibits migration and invasion of cancer cells in vitro .

top caption :

Lysine deficient protein kinase (WNK) signaling inhibitor

extended description :

Lysine deficient protein kinase (WNK) signaling inhibitor

chemical name text :

7-Ethoxy-N3-(2-furanylmethyl)-3,9-acridinediamine

formula :

C20H19N3O2

formula text :

C20H19N3O2

cas num :

332922-63-1

USD :

213 USD

product details :

Lysine deficient protein kinase (WNK) signaling inhibitor

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage