5565/10 | Tocris Bioscience 5565/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5565/10

catalog :

5565/10

quantity :

10 mg (also 50 mg)

price :

175 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rossi Sebastiano M, Pozzato C, Saliakoura M, Yang Z, Peng R, Galiè M, et al. ACSL3-PAI-1 signaling axis mediates tumor-stroma cross-talk promoting pancreatic cancer progression. Sci Adv. 2020;6: pubmed publisher

image

image 1 :

Cat.No. 5565 - Tiplaxtinin C24H16F3NO4 CAS No. 393105-53-8

product information

master code :

5565

SKU :

5565/10

product name :

Tiplaxtinin

unit size :

10 mg (also 50 mg)

description :

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

target :

PAI-1 Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

439.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Tiplaxtinin is a plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC50 = 2.7 M). Induces vascular smooth muscle cell apoptosis in vitro and reduces carotid artery neointimal formation in a rat vascular injury model. Promotes thrombolysis in rat and dog models of acute arterial thrombosis. Orally available.

top caption :

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

extended description :

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

chemical name text :

-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid

formula :

C24H16F3NO4

formula text :

C24H16F3NO4

cas num :

393105-53-8

USD :

175 USD

product details :

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

alt names :

PAI 039,tiplasinin

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage