BX 430 | Tocris Bioscience 5545 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BX 430

catalog :

5545

quantity :

10 mg (also 50 mg)

price :

169 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Datta G, Miller N, Afghah Z, Geiger J, Chen X. HIV-1 gp120 Promotes Lysosomal Exocytosis in Human Schwann Cells. Front Cell Neurosci. 2019;13:329 pubmed publisher

product information

brand :

Tocris

master code :

5545

SKU :

5545/10

product name :

BX 430

description :

Selective P2X4 allosteric antagonist

target :

P2X Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

413.11

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective P2X4 allosteric antagonist (IC50 = 0.54 M). Exhibits 10-fold selectivity for human P2X4 receptors over P2X1, P2X2, P2X3, P2X5 and P2X7 receptors. Binds noncompetitively at extracellular allosteric site. Effective at human and zebrafish, but not mouse and rat P2X4 receptors.

catalog number base :

5545

product keywords :

BX430 selective allosteric noncompetitive antagonists antaognism purinergic receptors purinoceptors P2X4 P2X Receptors 5545,

extended description :

Selective P2X4 allosteric antagonist

chemical name text :

N-[2,6-Dibromo-4-(1-methylethyl)phenyl]-N -(3-pyridinyl)urea

formula :

C 15 H 15 Br 2 N 3 O

formula text :

C15H15Br2N3O

cas num :

688309-70-8

2020 USD :

164

2021 USD :

169 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage