5522/10 | Tocris Bioscience 5522/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5522/10

catalog :

5522/10

quantity :

10 mg (also 50 mg)

price :

160 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5522 - Napabucasin C14H8O4 CAS No. 83280-65-3

product information

master code :

5522

SKU :

5522/10

product name :

Napabucasin

unit size :

10 mg (also 50 mg)

description :

STAT3 inhibitor; also blocks cancer stem cell self-renewal

target :

STAT Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

240.21

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Napabucasin is a STAT3 inhibitor. Blocks spherogenesis of cancer stem cells (CSC), but not hematopoietic stem cells. Inhibits PaCa-2 xenograft tumor growth in mice, even after cessation of treatment, and decreases population of CSCs in PaCa-2 tumors from treated mice. Also blocks spleen and liver metastases of colon cancer cells in a mouse model.

top caption :

STAT3 inhibitor; also blocks cancer stem cell self-renewal

extended description :

STAT3 inhibitor; also blocks cancer stem cell self-renewal

chemical name text :

2-Acetylnaphtho[2,3-b]furan-4,9-dione

formula :

C14H8O4

formula text :

C14H8O4

cas num :

83280-65-3

USD :

160 USD

product details :

STAT3 inhibitor; also blocks cancer stem cell self-renewal

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage