BIX NHE1 inhibitor | Tocris Bioscience 5512 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BIX NHE1 inhibitor

catalog :

5512

quantity :

10 mg (also 50 mg)

price :

169 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5512

SKU :

5512/10

product name :

BIX NHE1 inhibitor

description :

Potent and selective NHE1 inhibitor

target :

Na+/Ca2+ Exchanger Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

392.8

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective NHE1 inhibitor (IC50 = 31 nM). Selective for NHE1 over NHE2 and NHE3. Prevents ischemic damage in an ischemia reperfusion injury isolated rat heart model ex vivo . Prevents phenylephrine -induced cardiomyocyte hypertrophy in vitro , and attenuates cardiac hypertrophy and left ventricular dysfunction postinfarction in rats. Orally bioavailable.

catalog number base :

5512

product keywords :

BIXNHE1 inhibitor sodium hydrogen exchanger isoform1 inhibitors inhibits potent selective hypertrophy ischemia Na+/H+ Exchanger 5512,

extended description :

Potent and selective NHE1 inhibitor

chemical name text :

4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide hydrochloride

formula :

C 16 H 19 F 3 N 4 O 2 .HCl

formula text :

C16H19F3N4O2.HCl

cas num :

1422252-46-7

2020 USD :

164

2021 USD :

169 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage