5498/1 | Tocris Bioscience 5498/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5498/1

catalog :

5498/1

quantity :

1 mg

price :

339 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Shen G, Hu S, Zhao Z, Zhang L, Ma Q. C-Type Natriuretic Peptide Ameliorates Vascular Injury and Improves Neurological Outcomes in Neonatal Hypoxic-Ischemic Brain Injury in Mice. Int J Mol Sci. 2021;22: pubmed publisher
Sun F, Zhou K, Tian K, Zhang X, Liu W, Wang J, et al. Atrial Natriuretic Peptide Promotes Neurite Outgrowth and Survival of Cochlear Spiral Ganglion Neurons in vitro Through NPR-A/cGMP/PKG Signaling. Front Cell Dev Biol. 2021;9:681421 pubmed publisher

image

image 1 :

Cat.No. 5498 - AP 811 N2-[4-(2-Naphthoylamino)phenylacetyl]-Arg-Ile-Asp-Arg-(S)-2-methylbutylamide CAS No. 124833-45-0

product information

master code :

5498

SKU :

5498/1

product name :

AP 811

unit size :

1 mg

description :

High affinity, selective NPR3 antagonist

target :

Natriuretic Peptide Receptor Antagonists

category :

Peptides

purity :

95%

observed molecular weight :

915.1

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

AP 811 is a high affinity, selective ANP clearance receptor (NPR3) antagonist (Ki = 0.45 nM). Exhibits 20,000-fold selectivity for NPR3 over NPR1. Inhibits ANP-stimulated Na+/K+ pump activity in rabbit ventricular cardiomyocytes in vitro . Also blocks proliferation of rodent neonatal cardiomyocytes seen at low ANP concentrations in vitro .

top caption :

High affinity, selective NPR3 antagonist

extended description :

High affinity, selective NPR3 antagonist

formula :

C46H66N12O8

formula text :

C46H66N12O8

cas num :

124833-45-0

USD :

339 USD

product details :

High affinity, selective NPR3 antagonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage