5495/10 | Tocris Bioscience 5495/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5495/10

catalog :

5495/10

quantity :

10 mg (also 50 mg)

price :

333 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Li K, Huo Q, Dimmitt N, Qu G, Bao J, Pandya P, et al. Osteosarcoma-enriched transcripts paradoxically generate osteosarcoma-suppressing extracellular proteins. elife. 2023;12: pubmed publisher
Li K, Sun X, Minami K, Tamari K, Ogawa K, Li H, et al. Proteomes from AMPK-inhibited peripheral blood mononuclear cells suppress the progression of breast cancer and bone metastasis. Theranostics. 2023;13:1247-1263 pubmed publisher
Gingrich J, Pu Y, Veiga Lopez A. A modified parachute assay for assessment of gap junction intercellular communication in placental trophoblast cells. Toxicol Mech Methods. 2021;31:393-399 pubmed publisher
Gingrich J, Pu Y, Upham B, Hulse M, Pearl S, Martin D, et al. Bisphenol S enhances gap junction intercellular communication in ovarian theca cells. Chemosphere. 2021;263:128304 pubmed publisher

image

image 1 :

Cat.No. 5495 - CW 008 C21H14F2N6O2 CAS No. 1134613-19-6

product information

master code :

5495

SKU :

5495/10

product name :

CW 008

unit size :

10 mg (also 50 mg)

description :

PKA signaling activator; promotes osteogenesis from hMSCs

target :

Protein Kinase A Activators

category :

Small Molecules

purity :

98%

observed molecular weight :

420.37

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CW 008 is a cAMP/PKA/CREB pathway activator. Promotes osteogenic differentiation of human bone marrow-derived MSCs in vitro . Increases bone mass and bone volume density in ovariectomized mice.

top caption :

PKA signaling activator; promotes osteogenesis from hMSCs

extended description :

PKA signaling activator; promotes osteogenesis from hMSCs

chemical name text :

4-Fluoro-N-[5-fluoro-6-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]benzamide

formula :

C21H14F2N6O2

formula text :

C21H14F2N6O2

cas num :

1134613-19-6

USD :

333 USD

product details :

PKA signaling activator; promotes osteogenesis from hMSCs

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage