Aliskiren hemifumarate | Tocris Bioscience 5491 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Aliskiren hemifumarate

catalog :

5491

quantity :

10 mg (also 50 mg)

price :

201 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5491

SKU :

5491/10

product name :

Aliskiren hemifumarate

description :

Potent renin inhibitor; antihypertensive

target :

Additional Synthetic Protease Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

609.83

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent renin inhibitor (IC50 = 0.6 and 80 nM for human and rat respectively). Exhibits selectivity for renin over a range of other aspartic proteinases ( 5000 nM). Lowers blood pressure in a hypertensive rodent model. Orally active.

catalog number base :

5491

product keywords :

SPP100 Potent renin inhibitors inhibits hypertensive hypertension blood pressure heart SPP 100 Other Proteases Angiotensin-Converting Enzyme 5491,

extended description :

Potent renin inhibitor; antihypertensive

chemical name text :

( S, S, S, S)- -Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)- -hydroxy-4-methoxy-3-(3-methoxypropoxy)- , -bis(1-methylethyl)benzeneoctanamide hemifumarate

formula :

C 30 H 53 N 3 O6.1/2C 4 H 4 O 4

formula text :

C30H53N3O6.1/2C4H4O4

cas num :

173334-58-2

2020 USD :

195

2021 USD :

201 USD

alt names :

SPP 100

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage