5491/10 | Tocris Bioscience 5491/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5491/10

catalog :

5491/10

quantity :

10 mg (also 50 mg)

price :

254 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Su H, Liu N, Zhang Y, Kong J. Vitamin D/VDR regulates peripheral energy homeostasis via central renin-angiotensin system. J Adv Res. 2021;33:69-80 pubmed publisher

image

image 1 :

Cat.No. 5491 - Aliskiren hemifumarate C30H53N3O6.1/2C4H4O4 CAS No. 173334-58-2

product information

master code :

5491

SKU :

5491/10

product name :

Aliskiren hemifumarate

unit size :

10 mg (also 50 mg)

description :

Potent renin inhibitor; antihypertensive

target :

Additional Synthetic Protease Inhibitors

category :

Small Molecules

purity :

99%

observed molecular weight :

609.83

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Aliskiren hemifumarate is a potent renin inhibitor (IC50 = 0.6 and 80 nM for human and rat respectively). Exhibits selectivity for renin over a range of other aspartic proteinases ( 5000 nM). Lowers blood pressure in a hypertensive rodent model. Orally active.

top caption :

Potent renin inhibitor; antihypertensive

extended description :

Potent renin inhibitor; antihypertensive

chemical name text :

( S, S, S, S)- -Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)- -hydroxy-4-methoxy-3-(3-methoxypropoxy)- , -bis(1-methylethyl)benzeneoctanamide hemifumarate

formula :

C30H53N3O6.1/2C4H4O4

formula text :

C30H53N3O6.1/2C4H4O4

cas num :

173334-58-2

USD :

254 USD

product details :

Potent renin inhibitor; antihypertensive

alt names :

SPP 100

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage