5J 4 | Tocris Bioscience 5490 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5J 4

catalog :

5490

quantity :

10 mg (also 50 mg)

price :

169 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rao W, Peng C, Zhang L, Su N, Wang K, Hui H, et al. Homer1a attenuates glutamate-induced oxidative injury in HT-22 cells through regulation of store-operated calcium entry. Sci Rep. 2016;6:33975 pubmed publisher

product information

brand :

Tocris

master code :

5490

SKU :

5490/10

product name :

5J 4

description :

CRAC channel blocker; anti-inflammatory

target :

Other Calcium Channel Blockers

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

312.34

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Calcium release-activated calcium (CRAC) channel blocker. Blocks store-operated calcium entry (SOCE) in HeLa-O+S cells and Th17 cells in vitro . Ameliorates symptoms and reduces CNS infiltration by mononuclear cells in a mouse model of experimental autoimmune encephalomyelitis (EAE) in vivo .

catalog number base :

5490

product keywords :

5J4 CRAC calcium release activated store operated entry SOCE anti-inflammatory channels Ca2+ blockers Other Calcium Channels STIM-Orai Channels 5490,

extended description :

CRAC channel blocker; anti-inflammatory

chemical name text :

N-[[(6-Hydroxy-1-naphthalenyl)amino]thioxomethyl]-2-furancarboxamide

formula :

C 16 H 12 N 2 O 3 S

formula text :

C16H12N2O3S

cas num :

827001-82-1

2020 USD :

164

2021 USD :

169 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage