product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
5490/10
catalog :
5490/10
quantity :
10 mg (also 50 mg)
price :
213 USD
more info or order :
citations: 1
Reference
Rao W, Peng C, Zhang L, Su N, Wang K, Hui H, et al. Homer1a attenuates glutamate-induced oxidative injury in HT-22 cells through regulation of store-operated calcium entry. Sci Rep. 2016;6:33975 pubmed publisher
image
image 1 :
Tocris Bioscience 5490/10 image 1
Cat.No. 5490 - 5J 4 C16H12N2O3S CAS No. 827001-82-1
product information
master code :
5490
SKU :
5490/10
product name :
5J 4
unit size :
10 mg (also 50 mg)
description :
CRAC channel blocker; anti-inflammatory
target :
Other Calcium Channel Blockers
category :
Small Molecules
purity :
98%
observed molecular weight :
312.34
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
5J 4 is a calcium release-activated calcium (CRAC) channel blocker. Blocks store-operated calcium entry (SOCE) in HeLa-O+S cells and Th17 cells in vitro . Ameliorates symptoms and reduces CNS infiltration by mononuclear cells in a mouse model of experimental autoimmune encephalomyelitis (EAE) in vivo .
top caption :
CRAC channel blocker; anti-inflammatory
extended description :
CRAC channel blocker; anti-inflammatory
chemical name text :
N-[[(6-Hydroxy-1-naphthalenyl)amino]thioxomethyl]-2-furancarboxamide
formula :
C16H12N2O3S
formula text :
C16H12N2O3S
cas num :
827001-82-1
USD :
213 USD
product details :
CRAC channel blocker; anti-inflammatory
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK