product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
5474/10
catalog :
5474/10
quantity :
10 mg
price :
292 USD
more info or order :
citations: 7
Reference
Todorova V, Stauffacher M, Ravotto L, N xf6 tzli S, Karademir D, Ebner L, et al. Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation. Mol Neurodegener. 2023;18:15 pubmed publisher
Lim H, Hughes C, Lim M, Li J, Rakshit M, Yeo C, et al. Development of reconstructed intestinal micronucleus cytome (RICyt) assay in 3D human gut model for genotoxicity assessment of orally ingested substances. Arch Toxicol. 2022;96:1455-1471 pubmed publisher
Gaertner F, Reis Rodrigues P, de Vries I, Hons M, Aguilera J, Riedl M, et al. WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues. Dev Cell. 2022;57:47-62.e9 pubmed publisher
Ullo M, Logue J. ADF and cofilin-1 collaborate to promote cortical actin flow and the leader bleb-based migration of confined cells. elife. 2021;10: pubmed publisher
Shlevkov E, Basu H, Bray M, Sun Z, Wei W, Apaydin K, et al. A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport. Cell Rep. 2019;28:3224-3237.e5 pubmed publisher
Bernier L, Bohlen C, York E, Choi H, Kamyabi A, Dissing Olesen L, et al. Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia. Cell Rep. 2019;27:2895-2908.e4 pubmed publisher
Diaz Garcia C, Mongeon R, Lahmann C, Koveal D, Zucker H, Yellen G. Neuronal Stimulation Triggers Neuronal Glycolysis and Not Lactate Uptake. Cell Metab. 2017;26:361-374.e4 pubmed publisher
product information
master code :
5474
SKU :
5474/10
product name :
Cytochalasin B
unit size :
10 mg
description :
Inhibitor of actin polymerization
target :
Actin-related Products
category :
Small Molecules
purity :
98%
observed molecular weight :
479.61
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Cytochalasin B is an inhibitor of actin polymerization. Inhibits cell division, migration and glucose transport. Causes G2/M cell cycle arrest and apoptosis in HCT-116 colorectal carcinoma cells. Cell permeable.
top caption :
Inhibitor of actin polymerization
extended description :
Inhibitor of actin polymerization
chemical name text :
(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-6,7,8,9,10,12a,13,14,15,15a,16,17-Dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-2H-oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione
formula :
C29H37NO5
formula text :
C29H37NO5
cas num :
14930-96-2
USD :
292 USD
product details :
Inhibitor of actin polymerization
storage :
Store at -20░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK