PMX 53 | Tocris Bioscience 5473 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PMX 53

catalog :

5473

quantity :

1 mg

price :

250 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Liu H, Kim H, Deepak R, Wang L, Chung K, Fan H, et al. Orthosteric and allosteric action of the C5a receptor antagonists. Nat Struct Mol Biol. 2018;25:472-481 pubmed publisher

product information

brand :

Tocris

master code :

5473

SKU :

5473/1

product name :

PMX 53

description :

Potent C5a receptor antagonist

target :

Complement Signaling inhibitors

category :

Peptides

unit size :

1 mg

observed molecular weight :

896.1

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Potent C5a receptor antagonist (IC50 = 20 nM). Also MrgX2 agonist. Stimulates MrgX2-mediated mast cell degranulation. Also inhibits C5a-induced hypernociception in rats, inhibits lung metastasis in a mouse breast cancer model and reduces atherosclerotic lesions in a mouse model of atherosclerosis. . Negative Control also available.

catalog number base :

5473

product keywords :

PMX53 potent c5a complement system receptors antagonists mrgx2 mas-related agonists hypernociception MRGPRX2 Complement Mas-related G Protein-Coupled Receptors 5473,

extended description :

Potent C5a receptor antagonist

formula :

C 47 H 65 N 11 O 7

formula text :

C47H65N11O7

cas num :

219639-75-5

2020 USD :

245

2021 USD :

250 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage