CGP 60474 | Tocris Bioscience 5471 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CGP 60474

catalog :

5471

quantity :

10 mg (also 50 mg)

price :

169 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Jorda R, Hendrychova D, Voller J, Rezníčková E, Gucký T, Krystof V. How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases?. J Med Chem. 2018;61:9105-9120 pubmed publisher

product information

brand :

Tocris

master code :

5471

SKU :

5471/10

product name :

CGP 60474

description :

Potent cdk inhibitor

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

355.82

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent cyclin-dependent kinase (cdk) inhibitor (reported IC50 values are 3 - 80, 9.5, 13, 17 - 60, 200 and 220 nM for cdk2, cdk5, cdk9, cdk1, cdk4 and cdk7, respectively). Also inhibits PKC in the low micromolar range. Displays reversible G1/S cell cycle arrest in U2-OS cells.

catalog number base :

5471

product keywords :

CGP60474 dual cdk1cdk2 inhibitors inhibits cyclin dependent protein kinases Cyclin-dependent Kinase 5471,

extended description :

Potent cdk inhibitor

chemical name text :

3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol

formula :

C 18 H 18 ClN 5 O

formula text :

C18H18ClN5O

cas num :

164658-13-3

2020 USD :

164

2021 USD :

169 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage