5459/10 | Tocris Bioscience 5459/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5459/10

catalog :

5459/10

quantity :

10 mg (also 50 mg)

price :

239 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Pulakazhi Venu V, Alston L, Iftinca M, Tsai Y, Stephens M, Warriyar K V V, et al. Nr4A1 modulates inflammation-associated intestinal fibrosis and dampens fibrogenic signaling in myofibroblasts. Am J Physiol Gastrointest Liver Physiol. 2021;321:G280-G297 pubmed publisher

image

image 1 :

Cat.No. 5459 - Cytosporone B C18H26O5 CAS No. 321661-62-5

product information

master code :

5459

SKU :

5459/10

product name :

Cytosporone B

unit size :

10 mg (also 50 mg)

description :

High affinity Nur77 agonist

target :

Nuclear Receptor Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

322.4

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cytosporone B is a naturally occurring Nur77 (NR4A1) agonist (Kd = 8.52 x 10-7 M). Induces apoptosis in gastric cancer cells in vitro . Increases blood glucose levels in fasting C57 mice and suppresses xenograft tumor growth. Also exhibits a potent antifibrotic effect in bleomycin-induced skin fibrosis in vivo .

top caption :

High affinity Nur77 agonist

extended description :

High affinity Nur77 agonist

chemical name text :

Ethyl 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetate

formula :

C18H26O5

formula text :

C18H26O5

cas num :

321661-62-5

USD :

239 USD

product details :

High affinity Nur77 agonist

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage