Zosuquidar trihydrochloride | Tocris Bioscience 5456 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Zosuquidar trihydrochloride

catalog :

5456

quantity :

10 mg (also 50 mg)

price :

208 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5456

SKU :

5456/10

product name :

Zosuquidar trihydrochloride

description :

High affinity P-gp inhibitor

target :

Multidrug Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

636.99

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity P-glycoprotein (P-gp) inhibitor (Kd = 79 nM). Restores doxorubicin (Cat. No. 2252) sensitivity in P-gp-expressing multidrug (MDR) resistant cancer cell lines. Also potentiates antitumor efficacy of taxol (Cat. No. 1097) in a MDR human non-small cell lung carcinoma xenograft mouse model.

catalog number base :

5456

product keywords :

LY335979 RS33295198 high affinity p-glycoprotein p-gp inhibitors inhibits multidrug transporters resistance LY 335979 Multidrug Transporters 5456,

extended description :

High affinity P-gp inhibitor

chemical name text :

( R)-4-[(1a ,6 ,10b )-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]- -[(5-quinolinyloxy)methyl]-1-piperazineethanol trihydrochloride

formula :

C 32 H 31 F 2 N 3 O 2 .3HCl

formula text :

C32H31F2N3O2.3HCl

cas num :

167465-36-3

2020 USD :

201

2021 USD :

208 USD

alt names :

LY 335979

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage