SM 324405 | Tocris Bioscience 5445 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SM 324405

catalog :

5445

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5445

SKU :

5445/10

product name :

SM 324405

description :

Potent TLR7 agonist

target :

Toll-like Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

385.42

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent TLR7 agonist (EC50 = 50 nM). Exhibits selectivity for TLR7 over TLR8. Induces IFN- and - expression in human PBMCs and mouse splenocytes, and inhibits IL-5 production in human PBMCs in vitro . Rapidly metabolized to acid metabolite (t = 2.6 min in human plasma).

catalog number base :

5445

product keywords :

SM324405 toll-like receptors TLR7 potent agonists agonism Toll-like Receptors 5445,

extended description :

Potent TLR7 agonist

chemical name text :

Methyl 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]benzeneacetate

formula :

C 19 H 23 N 5 O 4

formula text :

C19H23N5O4

cas num :

677773-91-0

2020 USD :

205

2021 USD :

205 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage