Heclin | Tocris Bioscience 5433 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Heclin

catalog :

5433

quantity :

10 mg (also 50 mg)

price :

151 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Yang C, Hsu H, Chang H, Lee Y, Lee S. Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na+/K+-ATPase independent proteolysise. Biochem Pharmacol. 2020;180:114122 pubmed publisher

product information

brand :

Tocris

master code :

5433

SKU :

5433/10

product name :

Heclin

description :

HECT E3 ubiquitin ligase inhibitor

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

283.32

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

HECT E3 ubiquitin ligase inhibitor; inhibits Nedd4, Smurf2 and WWP1 (IC50 values are 6.3, 6.8 and 6.9 M respectively). Selective for HECT-mediated over RING-mediated ubiquitination.

catalog number base :

5433

product keywords :

E6-AP carboxyl terminus HECT E3 ubiquitin ubiquitination inhibitors inhibits inhibts NAMs negative allosteric modulators Ubiquitin E3 Ligases 5433, E3 Ligase

extended description :

HECT E3 ubiquitin ligase inhibitor

chemical name text :

N-(4-Acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide

formula :

C 17 H 17 NO 3

formula text :

C17H17NO3

cas num :

890605-54-6

2020 USD :

145

2021 USD :

151 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage