R 7050 | Tocris Bioscience 5432 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

R 7050

catalog :

5432

quantity :

10 mg (also 50 mg)

price :

162 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gonzalez Juarbe N, Bradley K, Shenoy A, Gilley R, Reyes L, Hinojosa C, et al. Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia. Cell Death Differ. 2017;24:917-928 pubmed publisher

product information

brand :

Tocris

master code :

5432

SKU :

5432/10

product name :

R 7050

description :

Inhibitor of TNF- receptor 1 signaling

target :

Additional Cytokine Receptor Products

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

380.77

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of TNF- receptor 1 (TNFR1) signaling; blocks TNFR1 association with TRADD and RIP1. Inhibits TNF- -induced NF- B and MAPK signaling pathway activation. Attenuates intracerebral hemorrhage-induced neurovascular injury in mice.

catalog number base :

5432

product keywords :

R7050 tumor necrosis TNFa TNFalpha TNF inhibitors inhibits signaling cytokines receptors Cytokine Receptors 5432,

extended description :

Inhibitor of TNF- receptor 1 signaling

chemical name text :

8-Chloro-4-(phenylthio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline

formula :

C 16 H 8 ClF 3 N 4 S

formula text :

C16H8ClF3N4S

cas num :

303997-35-5

2020 USD :

155

2021 USD :

162 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage