5432/10 | Tocris Bioscience 5432/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5432/10

catalog :

5432/10

quantity :

10 mg

price :

205 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Arenas Y, Mart xed nez Garc xed a M, Llansola M, Felipo V. Enhanced BDNF and TrkB Activation Enhance GABA Neurotransmission in Cerebellum in Hyperammonemia. Int J Mol Sci. 2022;23: pubmed publisher
Orapiriyakul W, Tsimbouri M, Childs P, Campsie P, Wells J, Fernández Yague M, et al. Nanovibrational Stimulation of Mesenchymal Stem Cells Induces Therapeutic Reactive Oxygen Species and Inflammation for Three-Dimensional Bone Tissue Engineering. ACS Nano. 2020;14:10027-10044 pubmed publisher
Gonzalez Juarbe N, Bradley K, Shenoy A, Gilley R, Reyes L, Hinojosa C, et al. Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia. Cell Death Differ. 2017;24:917-928 pubmed publisher

image

image 1 :

Cat.No. 5432 - R 7050 C16H8ClF3N4S CAS No. 303997-35-5

product information

master code :

5432

SKU :

5432/10

product name :

R 7050

unit size :

10 mg

description :

Inhibitor of TNF- receptor 1 signaling

target :

Additional Cytokine Receptor Products

category :

Small Molecules

purity :

98%

observed molecular weight :

380.77

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

R 7050 is an inhibitor of TNF- receptor 1 (TNFR1) signaling; blocks TNFR1 association with TRADD and RIP1. Inhibits TNF- -induced NF- B and MAPK signaling pathway activation. Attenuates intracerebral hemorrhage-induced neurovascular injury in mice.

top caption :

Inhibitor of TNF- receptor 1 signaling

extended description :

Inhibitor of TNF- receptor 1 signaling

chemical name text :

8-Chloro-4-(phenylthio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline

formula :

C16H8ClF3N4S

formula text :

C16H8ClF3N4S

cas num :

303997-35-5

USD :

205 USD

product details :

Inhibitor of TNF- receptor 1 signaling

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage