SR 13800 | Tocris Bioscience 5431 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SR 13800

catalog :

5431

quantity :

10 mg (also 50 mg)

price :

216 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Maacha S, Hong J, von Lersner A, Zijlstra A, Belkhiri A. AXL Mediates Esophageal Adenocarcinoma Cell Invasion through Regulation of Extracellular Acidification and Lysosome Trafficking. Neoplasia. 2018;20:1008-1022 pubmed publisher
Liu L, MacKenzie K, Putluri N, Maletic Savatic M, Bellen H. The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D. Cell Metab. 2017;26:719-737.e6 pubmed publisher

product information

brand :

Tocris

master code :

5431

SKU :

5431/10

product name :

SR 13800

description :

Potent MCT1 inhibitor

target :

Monocarboxylate Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

435.58

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent MCT1 inhibitor (IC50 = 0.5 nM); blocks proliferation of Raji lymphoma cells in vitro . Also inhibits lactate uptake in breast cancer cells in vitro .

catalog number base :

5431

product keywords :

SR13800 potent MCT1 inhibitors inhibits lactate uptake anticancer antitumour antitumor SLC16A1 monocarboxylate transporters Monocarboxylate Transporters 5431,

extended description :

Potent MCT1 inhibitor

chemical name text :

2,6-Dihydro-7-[(3-hydroxypropyl)thio]-2-methyl-4-(2-methylpropyl)-6-(1-naphthalenylmethyl)-1H-pyrrolo[3,4-d]pyridazin-1one

formula :

C 25 H 29 N 3 O 2 S

formula text :

C25H29N3O2S

cas num :

227321-12-2

2020 USD :

207

2021 USD :

216 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage