NG 25 | Tocris Bioscience 5429 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NG 25

catalog :

5429

quantity :

5 mg

price :

325 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5429

SKU :

5429/5

product name :

NG 25

description :

TGF- -activated kinase (TAK1) inhibitor

target :

Other Kinase Inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

98%

observed molecular weight :

537.58

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TGF- -activated kinase (TAK1) inhibitor (IC50 = 149 nM). Also inhibits LYN, MAP4K2 and Abl kinase activity (IC50 values are 12.9, 21.7 and 75.2 nM, respectively). Suppresses CpG A and CpG B-stimulated secretion of IFN- and TLR7/8 agonist CL097-stimulated secretion of IFN- in Gen 2.2 leukemia cells in vitro .

catalog number base :

5429

product keywords :

NG25 TAK1 TGFbeta TGFb TGF activated kinases inhibitors inhibits MAP4K2 LYN Abl Other Kinases 5429,

extended description :

TGF- -activated kinase (TAK1) inhibitor

chemical name text :

N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide

formula :

C 29 H 30 F 3 N 5 O 2

formula text :

C29H30F3N5O2

cas num :

1315355-93-1

2020 USD :

315

2021 USD :

325 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage