TGN 020 | Tocris Bioscience 5425 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TGN 020

catalog :

5425

quantity :

10 mg (also 50 mg)

price :

115 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Harrison I, Ismail O, Machhada A, Colgan N, Ohene Y, Nahavandi P, et al. Impaired glymphatic function and clearance of tau in an Alzheimer's disease model. Brain. 2020;143:2576-2593 pubmed publisher
Wang S, Wang S, Asgar J, Joseph J, Ro J, Wei F, et al. Ca2+ and calpain mediate capsaicin-induced ablation of axonal terminals expressing transient receptor potential vanilloid 1. J Biol Chem. 2017;292:8291-8303 pubmed publisher

product information

brand :

Tocris

master code :

5425

SKU :

5425/10

product name :

TGN 020

description :

Aquaporin 4 (AQP4) channel blocker

target :

Ion Channel Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

206.22

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Aquaporin 4 (AQP4) channel blocker (IC50 = 3.1 M). Increases regional cerebral blood flow and reduces ischemia-induced brain edema in mice.

catalog number base :

5425

product keywords :

TGN020 aquaporin AQP4 channels blockers ischemia Aquaporins 5425,

extended description :

Aquaporin 4 (AQP4) channel blocker

chemical name text :

N-1,3,4-Thiadiazol-2-yl-3-pyridinecarboxamide

formula :

C 8 H 6 N 4 OS

formula text :

C8H6N4OS

cas num :

51987-99-6

2020 USD :

110

2021 USD :

115 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage