5425/10 | Tocris Bioscience 5425/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5425/10

catalog :

5425/10

quantity :

10 mg (also 50 mg)

price :

151 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Li Y, Chen M, Hu J, Sheng R, Lin Q, He X, et al. Volumetric Compression Induces Intracellular Crowding to Control Intestinal Organoid Growth via Wnt/β-Catenin Signaling. Cell Stem Cell. 2021;28:63-78.e7 pubmed publisher
Harrison I, Ismail O, Machhada A, Colgan N, Ohene Y, Nahavandi P, et al. Impaired glymphatic function and clearance of tau in an Alzheimer's disease model. Brain. 2020;143:2576-2593 pubmed publisher
Wang S, Wang S, Asgar J, Joseph J, Ro J, Wei F, et al. Ca2+ and calpain mediate capsaicin-induced ablation of axonal terminals expressing transient receptor potential vanilloid 1. J Biol Chem. 2017;292:8291-8303 pubmed publisher

product information

master code :

5425

SKU :

5425/10

product name :

TGN 020

unit size :

10 mg (also 50 mg)

description :

Aquaporin 4 (AQP4) channel blocker

target :

Aquaporin Channel Blockers

category :

Small Molecules

purity :

98%

observed molecular weight :

206.22

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TGN 020 is an aquaporin 4 (AQP4) channel blocker (IC50 = 3.1 M). Increases regional cerebral blood flow and reduces ischemia-induced brain edema in mice.

top caption :

Aquaporin 4 (AQP4) channel blocker

extended description :

Aquaporin 4 (AQP4) channel blocker

chemical name text :

N-1,3,4-Thiadiazol-2-yl-3-pyridinecarboxamide

formula :

C8H6N4OS

formula text :

C8H6N4OS

cas num :

51987-99-6

USD :

151 USD

product details :

Aquaporin 4 (AQP4) channel blocker

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage