BMH 21 | Tocris Bioscience 5417 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BMH 21

catalog :

5417

quantity :

10 mg (also 50 mg)

price :

215 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
McCullough K, Daskalakis N, Gafford G, Morrison F, Ressler K. Cell-type-specific interrogation of CeA Drd2 neurons to identify targets for pharmacological modulation of fear extinction. Transl Psychiatry. 2018;8:164 pubmed publisher

product information

brand :

Tocris

master code :

5417

SKU :

5417/10

product name :

BMH 21

description :

RNA polymerase I inhibitor; also p53 pathway activator

target :

RNA/DNA Polymerase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

360.41

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

p53 pathway activator; induces expression of p53 target genes. Also RNA polymerase 1 inhibitor; promotes degradation of RPA194. Reduces viability of multiple tumor cell lines and attenuates tumor growth of A375 melanoma cell xenografts in mice.

catalog number base :

5417

product keywords :

BMH21 p53 pathway activators rna polymerase inhibitors inhibits RPA194 antitumor DNA, RNA and Protein Synthesis RNA Polymerase p53 5417,

extended description :

RNA polymerase I inhibitor; also p53 pathway activator

chemical name text :

N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide

formula :

C 21 H 20 N 4 O 2

formula text :

C21H20N4O2

cas num :

896705-16-1

2020 USD :

210

2021 USD :

215 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage