5417/10 | Tocris Bioscience 5417/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5417/10

catalog :

5417/10

quantity :

10 mg (also 50 mg)

price :

241 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
McCullough K, Daskalakis N, Gafford G, Morrison F, Ressler K. Cell-type-specific interrogation of CeA Drd2 neurons to identify targets for pharmacological modulation of fear extinction. Transl Psychiatry. 2018;8:164 pubmed publisher

image

image 1 :

Cat.No. 5417 - BMH 21 C21H20N4O2 CAS No. 896705-16-1

product information

master code :

5417

SKU :

5417/10

product name :

BMH 21

unit size :

10 mg (also 50 mg)

description :

RNA polymerase I inhibitor; also p53 pathway activator

target :

RNA/DNA Polymerase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

360.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BMH 21 is a p53 pathway activator; induces expression of p53 target genes. Also RNA polymerase 1 inhibitor; promotes degradation of RPA194. Reduces viability of multiple tumor cell lines and attenuates tumor growth of A375 melanoma cell xenografts in mice.

top caption :

RNA polymerase I inhibitor; also p53 pathway activator

extended description :

RNA polymerase I inhibitor; also p53 pathway activator

chemical name text :

N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide

formula :

C21H20N4O2

formula text :

C21H20N4O2

cas num :

896705-16-1

USD :

241 USD

product details :

RNA polymerase I inhibitor; also p53 pathway activator

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage