5410/10 | Tocris Bioscience 5410/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5410/10

catalog :

5410/10

quantity :

10 mg (also 50 mg)

price :

272 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Diver M, Cheng Y, Julius D. Structural insights into TRPM8 inhibition and desensitization. Science. 2019;365:1434-1440 pubmed publisher

image

image 1 :

Cat.No. 5410 - TC-I 2014 C23H19F6N3O CAS No. 1221349-53-6

product information

master code :

5410

SKU :

5410/10

product name :

TC-I 2014

unit size :

10 mg (also 50 mg)

description :

Potent TRPM8 antagonist

target :

TRPM Blockers

category :

Small Molecules

purity :

98%

observed molecular weight :

467.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TC-I 2014 is a potent TRPM8 antagonist (IC50 values are 0.8, 3.0 and 4.4 nM for canine, human and rat channels respectively). Exhibits antiallodynic properties in pain models in vivo .

top caption :

Potent TRPM8 antagonist

extended description :

Potent TRPM8 antagonist

chemical name text :

3-[7-(Trifluoromethyl)-5-[2-(trifluoromethyl)phenyl]-1H-benzimidazol-2-yl]-1-oxa-2-azaspiro[4.5]dec-2-ene

formula :

C23H19F6N3O

formula text :

C23H19F6N3O

cas num :

1221349-53-6

USD :

272 USD

product details :

Potent TRPM8 antagonist

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage