5408/10 | Tocris Bioscience 5408/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5408/10

catalog :

5408/10

quantity :

10 mg (also 50 mg)

price :

349 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5408 - Ispinesib C30H33ClN4O2 CAS No. 336113-53-2

product information

master code :

5408

SKU :

5408/10

product name :

Ispinesib

unit size :

10 mg (also 50 mg)

description :

High affinity and selective allosteric KSP inhibitor

target :

Kinesin Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

517.06

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ispinesib is a high affinity allosteric kinesin spindle protein (KSP) inhibitor (Ki app = 1.7 nM). Exhibits 10,000-fold selectivity for KSP over a range of other mitotic kinesins. Inhibits proliferation and induces apoptosis of prostate and breast cancer cells in vitro . Induces tumor regression of breast cancer cell xenografts in mice.

top caption :

High affinity and selective allosteric KSP inhibitor

extended description :

High affinity and selective allosteric KSP inhibitor

chemical name text :

N-(3-Aminopropyl)-N-[(1R)-1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]-2-methylpropyl]-4-methylbenzamide

formula :

C30H33ClN4O2

formula text :

C30H33ClN4O2

cas num :

336113-53-2

USD :

349 USD

product details :

High affinity and selective allosteric KSP inhibitor

alt names :

SB 715992

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage