GA3-AM | Tocris Bioscience 5407 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GA3-AM

catalog :

5407

quantity :

10 mg (also 50 mg)

price :

72 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5407

SKU :

5407/10

product name :

GA3-AM

description :

Gibberellin-analog (GA3) chemical dimerizer; cell permeable

target :

Protein Dimerizers

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

90%

observed molecular weight :

418.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Gibberellin-analog (GA3) chemical dimerizer; induces rapid dimerization of GAIs and GID1. GA3-AM crosses the plasma membrane, is cleaved by cytosolic esterase releasing GA3, which then binds GID1- this complex then in turn forms a complex with GAI; this system works on a timescale of seconds (EC50 = 310 nM). GA3 and rapamycin (Cat. No. 1292) chemically inducible dimerization systems are orthogonal. Cell permeable.

catalog number base :

5407

product keywords :

Chemical dimerizer cell permeable chemically inducible dimerization system Biochemicals and Molecular Biology Protein Dimerizers 5407,

extended description :

Gibberellin-analog (GA3) chemical dimerizer; cell permeable

chemical name text :

(1S,2S,4aR,4bR,7S,9aS,10S,10aR)-1,2,4b,5,6,7,8,9,10,10a-Decahydro-2,7-dihydroxy-1-methyl-8-methylene-13-oxo-4a,1-(epoxymethano)-7,9a-methanobenz[a]azulene-10-acetic acid (acetyloxy)methyl ester

formula :

C 22 H 26 O 8

formula text :

C22H26O8

cas num :

1373154-68-7

2020 USD :

2021 USD :

72 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage