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company name :
Tocris Bioscience
product type :
chemical
product name :
(S)-PFI 2 hydrochloride
catalog :
5400
quantity :
10 mg
price :
221 USD
more info or order :
citations: 1
Reference
Judson R, Quarta M, Oudhoff M, Soliman H, Yi L, Chang C, et al. Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential. Cell Stem Cell. 2018;22:177-190.e7 pubmed publisher
product information
brand :
Tocris
master code :
5400
SKU :
5400/10
product name :
(S)-PFI 2 hydrochloride
description :
Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
target :
Lysine Methyltransferase Inhibitors
category :
Small Molecules
unit size :
10 mg
purity :
97%
observed molecular weight :
535.98
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Negative control of ( R )-PFI 2 hydrochloride . Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 M) compared to the active enantiomer. . Active Analog also available.
catalog number base :
5400
product keywords :
(S)-PFI2 HCl potent selective inhibitors inhibits SETD7 lysine histone methyltransferase epigenetics Hippo YAP negative control Lysine Methyltransferases Other Lysine Methyltransferases 5400,
extended description :
Negative control of (R)-PFI 2 hydrochloride (Cat. No. 4892)
chemical name text :
8-Fluoro-1,2,3,4-tetrahydro-N-[(1S)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-6-isoquinolinesulfonamide hydrochloride
formula :
C 23 H 25 F 4 N 3 O 3 S.HCl
formula text :
C23H25F4N3O3S.HCl
cas num :
1627607-88-8
2020 USD :
315
2021 USD :
221 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK