A01 | Tocris Bioscience 5397 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

A01

catalog :

5397

quantity :

10 mg (also 50 mg)

price :

168 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5397

SKU :

5397/10

product name :

A01

description :

High affinity Smurf1 inhibitor; enhances BMP signaling

target :

Ubiquitin Ligase (E3) Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

512.93

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM). Attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Potentiates BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells.

catalog number base :

5397

product keywords :

A01 bone morphogenetic proteins high affinity smurf1 e3 ubiquitin ligase inhibitors inhibits smad osteoblasts BMP and Other Activin Receptors Ubiquitin E3 Ligases 5397, E3 Ligase

extended description :

High affinity Smurf1 inhibitor; enhances BMP signaling

chemical name text :

[4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone

formula :

C 22 H 20 ClF 3 N 4 O 3 S

formula text :

C22H20ClF3N4O3S

cas num :

1007647-73-5

2020 USD :

163

2021 USD :

168 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage