ERK5-IN-1 | Tocris Bioscience 5393 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ERK5-IN-1

catalog :

5393

quantity :

10 mg (also 50 mg)

price :

273 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5393

SKU :

5393/10

product name :

ERK5-IN-1

description :

Potent and selective ERK5 inhibitor

target :

ERK Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

638.8

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective ERK5 inhibitor; inhibits EGFR-induced ERK5 autophosphorylation (EC50 = 90 nM) and ERK5 enzymatic activity (IC50 = 162 nM). Exhibits at least 30-fold selectivity for ERK5 over LRRK2 in a cell based assay. Also selective for ERK5 over a panel of other kinases. Orally bioavailable.

catalog number base :

5393

product keywords :

potent selective ERK5 extracellular regulated kinases MAPK7 inhibitors inhibits ERK 5393,

extended description :

Potent and selective ERK5 inhibitor

chemical name text :

11-Cyclopentyl-2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dihydro-5-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one

formula :

C 36 H 46 N 8 O 3

formula text :

C36H46N8O3

cas num :

1435488-37-1

2020 USD :

267

2021 USD :

273 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage