5380/10 | Tocris Bioscience 5380/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5380/10

catalog :

5380/10

quantity :

10 mg (also 50 mg)

price :

196 USD

more info or order :

Tocris Bioscience product webpage

product information

master code :

5380

SKU :

5380/10

product name :

ML 297

unit size :

10 mg (also 50 mg)

description :

Selective Kir3.1/3.2 (GIRK1/2) channel activator

target :

Inward Rectifier Potassium Channel Activators

category :

Small Molecules

purity :

99%

observed molecular weight :

328.32

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ML 297 is a selective Kir3.1/3.2 (GIRK1/2) channel activator (IC50 values are 160, 887 and 914 nM for GIRK1/2, GIRK1/4 and GIRK1/3 respectively). Exhibits no effect on GIRK2, GIRK2/3, Kir2.1 and Kv7.4 channels, and has minimal effect on a panel of other ion channels, receptors and transporters. Prevents PTZ -induced epileptic seizures in mice. Brain penetrant.

top caption :

Selective Kir3.1/3.2 (GIRK1/2) channel activator

extended description :

Selective Kir3.1/3.2 (GIRK1/2) channel activator

chemical name text :

N-(3,4-Difluorophenyl)-N -(3-methyl-1-phenyl-1H-pyrazol-5-yl)urea

formula :

C17H14F2N4O

formula text :

C17H14F2N4O

cas num :

1443246-62-5

USD :

196 USD

product details :

Selective Kir3.1/3.2 (GIRK1/2) channel activator

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage