VU 0422288 | Tocris Bioscience 5378 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

VU 0422288

catalog :

5378

quantity :

10 mg (also 50 mg)

price :

205 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

5378

SKU :

5378/10

product name :

VU 0422288

description :

Selective positive allosteric modulator of group III mGlu receptors

target :

Group III mGluR Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

360.19

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Group III mGlu receptor positive allosteric modulator (EC50 values are 108, 125 and 146 nM for mGlu4, mGlu8 and mGlu7 respectively). Exhibits selectivity over a panel of 68 other GPCRs, ion channels and transporters. Potentiates mGlu7-mediated reductions in excitatory post synaptic potentials in hippocampal slices.

catalog number base :

5378

product keywords :

VU0422288 ML396 groupIII mglu4 mglu8 mglu7 metabotropic receptors positive allosteric modulators selective PAM ML 396 Glutamate (Metabotropic) Group III Receptors 5378,

extended description :

Selective positive allosteric modulator of group III mGlu receptors

chemical name text :

N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide

formula :

C 17 H 11 Cl 2 N 3 O 2

formula text :

C17H11Cl2N3O2

cas num :

1630936-95-6

2020 USD :

199

2021 USD :

205 USD

alt names :

ML 396

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage