5378/10 | Tocris Bioscience 5378/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5378/10

catalog :

5378/10

quantity :

10 mg (also 50 mg)

price :

258 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 5378 - VU 0422288 C17H11Cl2N3O2 CAS No. 1630936-95-6

product information

master code :

5378

SKU :

5378/10

product name :

VU 0422288

unit size :

10 mg (also 50 mg)

description :

Selective positive allosteric modulator of group III mGlu receptors

target :

Group III mGluR Modulators

category :

Small Molecules

purity :

98%

observed molecular weight :

360.19

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

VU 0422288 is a group III mGlu receptor positive allosteric modulator (EC50 values are 108, 125 and 146 nM for mGlu4, mGlu8 and mGlu7 respectively). Exhibits selectivity over a panel of 68 other GPCRs, ion channels and transporters. Potentiates mGlu7-mediated reductions in excitatory post synaptic potentials in hippocampal slices.

top caption :

Selective positive allosteric modulator of group III mGlu receptors

extended description :

Selective positive allosteric modulator of group III mGlu receptors

chemical name text :

N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide

formula :

C17H11Cl2N3O2

formula text :

C17H11Cl2N3O2

cas num :

1630936-95-6

USD :

258 USD

product details :

Selective positive allosteric modulator of group III mGlu receptors

alt names :

ML 396

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage