chemical

SGC 707

5367

10 mg (also 50 mg)

180 USD

5367

5367/10

SGC 707

Potent and selective allosteric inhibitor of PRMT3

Protein Arginine Methyltransferase Inhibitors

Small Molecules

10 mg (also 50 mg)

98%

298.34

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Potent allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) (IC50 = 31 nM). Inhibits PRMT3-mediated methyltransferase activity in vitro . Displays 100-fold selectivity against 31 other methyltransferases and 250 other non-epigenetic targets. Decreases H4R3me2a levels in HEK293 cells in vitro . . Negative control also available.

5367

SGC707 Potent allosteric inhibitors inhibits of protein arginine methyltransferase 3 PRMT3 Protein Arginine Methyltransferases 5367,

Potent and selective allosteric inhibitor of PRMT3

1-(Isoquinolin-6-yl)-3-[2-oxo-2-(pyrrolidin-1-yl)ethyl] urea

C 16 H 18 N 4 O 2

C16H18N4O2

176

180 USD

Store at +4°C